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研究業績

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  1. Melatonin Mitigates Oxidative Damage and Apoptosis in Mouse Cerebellum Induced by High-LET 56Fe Particle Irradiation
    Kailash Manda, Megumi Ueno, and Kazunori Anzai
    J. Pineal Res., in press (2008). DOI: 10.1111/j.1600-079X.2007.00507.x
  2. Effect of Methyl Substitution on Antioxidative Property and Genotoxicity of Resveratrol
    Kiyoshi Fukuhara, Ikuo Nakanishi, Atsuko Matsuoka, Tomohiro Matsumura, Sachiko Honda, Mikiko Hayashi, Toshihiko Ozawa, Naoki Miyata, Shinichi Saito, Nobuo Ikota, and Haruhiro Okuda
    Chem. Res. Toxicol., 21, in press (2008). DOI: 10.1021/tx7003008
  3. Enhanced Radical-Scavenging Activity of Naturally-Oriented Artepillin C Derivatives
    Sushma Manda, Ikuo Nakanishi, Kei Ohkubo, Yoshihiro Uto, Tomonori Kawashima, Kiyoshi Fukuhara, Haruhiro Okuda, Hitoshi Hori, Toshihiko Ozawa, Nobuo Ikota, Shunichi Fukuzumi, and Kazunori Anzai
    Chem. Commun., 2008, in press. DOI: 10.1039/b715973k
  4. Evaluation of Sub-Microsecond Recovery Resonators for in vivo Electron Paramagnetic Resonance Imaging
    F. Hyodo, S. Subramanian, N. Devasahayam, R. Murugesan, K. Matsumoto, J. B. Mitchell, and M. C. Krishna
    J. Magn. Reson., in press (2008). DOI: 10.1016/j.jmr.2007.11.004
  5. Sucrose Radical-Production Cross-Section Regarding Heavy-Ion Irradiation
    Kouichi Nakagawa, Nobuo Ikota, and Kazunori Anzai
    Spectrochim. Acta, Part A, in press (2008). DOI: 10.1016/j.saa.2007.09.04
  6. Monitoring Redox-Sensitive Paramagnetic Contrast Agent by EPRI, OMRI and MRI
    Fuminori Hyodo, Ramachandran Murugesan, Ken-ichiro Matsumoto, Emi Hyodo, Sankaran Subramanian, James B. Mitchell, and Murali C. Krishna
    J. Magn. Reson., 190 (1), 105-112 (2008). DOI: 10.1016/j.jmr.2007.10.013
  7. Nitroxy Radicals: Electrochemical Redox Behaviour and Structure-Activity Relationships
    Sushma Manda, Ikuo Nakanishi, Kei Ohkubo, Haruko Yakumaru, Ken-ichiro Matsumoto, Toshihiko Ozawa, Nobuo Ikota, Shunichi Fukuzumi, and Kazunori Anzai
    Org. Biomol. Chem., 5 (24), 3951-3955 (2007). DOI: 10.1039/b714765a
  8. AFMK, a Melatonin Metabolite, Attenuates X-Ray-Induced Oxidative Damage to DNA, Proteins and Lipids in Mice
    Kailash Manda, Megumi Ueno, and Kazunori Anzai
    J. Pineal Res., 42 (4), 386-393 (2007). DOI: 10.1111/j.1600-079X.2007.00432.x
  9. Impact of Arsenic in Foodstuffs on the People Living in the Arsenic -Affected Areas of West Bengal, India
    Badal. K. Mandal, Kazuo T. Suzuki, and Kazunori Anzai
    J. Environ. Sci. Health, Part A, Toxic/Hazard. Subst. Environ. Eng., 42 (12), 1741-1752 (2007). DOI: 10.1080/10934520701564244
  10. Melatonin Attenuates Radiation-Induced Learning Deficit and Brain Oxidative Stress in Mice
    K. Manda, K. Anzai, S. Kumari, A. L. Bhatia
    Acta Neurobiol. Exp., 67, 63-70 (2007).
  11. Involvement of Electron Transfer in the Radical-Scavenging Reaction of Resveratrol
    Ikuo Nakanishi, Tomokazu Shimada, Kei Ohkubo, Sushma Manda, Takehiko Shimizu, Shiro Urano, Haruhiro Okuda, Naoki Miyata, Toshihiko Ozawa, Kazunori Anzai, Shunichi Fukuzumi, Nobuo Ikota, and Kiyoshi Fukuhara
    Chem. Lett., 36 (10), 1276-1277 (2007). DOI: 10.1246/cl.2007.1276
  12. A Long-Lived o-Semiquinone Radical Anion is Formed from N-b-alanyl-5-S-glutathyonyl-3,4-dihydroxyphenylalanine (5-S-GAD), an Insect-derived Antibacterial Substance
    Nobuko Akiyama, Ikuo Nakanishi, Kei Ohkubo, Kazue Satoh, Koichiro Tsuchiya, Takeshi Nishikawa, Shunichi Fukuzumi, Nobuo Ikota, Toshihiko Ozawa, Masafumi Tsujimoto, and Shunji Natori
    J. Biochem., 142 (1), 41-48 (2007). DOI: 10.1093/jb/mvm101
  13. Continuous Wave EPR Oximetric Imaging at 300 MHz Using Radiofrequency Power Saturation Effects
    Y. Hama, K. Matsumoto, R. Murugesan, S. Subramanian, N. Devasahayam, J. W. Koscielniak, F. Hyodo, J. A. Cook, J. B. Mitchell, M. C. Krishna
    Antioxid. Redox Signal., 9, 1709-1716 (2007).
  14. Spatially Resolved Biological Information from in vivo EPRI, OMRI, and MRI
    K. Matsumoto, S. Subramanian, R. Murugesan, J. B. Mitchell, M. C. Krishna
    Antioxid. Redox Signal., 9, 1125-1141 (2007).
  15. Effect of Solvent Polarity on the One-Electron Oxidation of Cyclic Nitroxyl Radicals
    Sushma Manda, Ikuo Nakanishi, Kei Ohkubo, Tomonori Kawashima, Ken-ichiro Matsumoto, Toshihiko Ozawa, Shunichi Fukuzumi, Nobuo Ikota, and Kazunori Anzai
    Chem. Lett., 36 (7), 914-915 (2007). DOI: 10.1246/cl.2007.914
  16. Scandium Ion-accelerated Scavenging Reaction of Cumylperoxyl Radical by a Cyclic Nitroxyl Radical via Electron Transfer
    Ikuo Nakanishi, Kumiko Kawaguchi, Kei Ohkubo, Tomonori Kawashima, Sushma Manda, Hideko Kanazawa, Keizo Takeshita, Kazunori Anzai, Toshihiko Ozasa, Shunichi Fukuzumi, and Nobuo Ikota
    Chem. Lett., 36 (3), 378-379 (2007). DOI: 10.1246/cl.2007.378
  17. Comparison of EPR Imaging and T1-Weighted MRI for Efficient Imaging of Nitroxyl Contrast Agents
    K. Matsumoto, M. Narazaki, H. Ikehira, K. Anzai, N. Ikota
    Magn. Reson., 187, 155-162 (2007)

  18. Feeding Period of Selenium-Deficient Diet and Response of Redox Relating Minerals
    Ken-ichiro Matsumoto, Marie Ariyoshi, Sachiyo Terada, Aya Okajo, Hiromi Urata, Yasunobu Sakuma, Kazue Satoh, Fusao Ushio, masamichi Tsukada, and Kazutoyo Endo
    J. Health Sci., 52 (6), 694-702 (2006).
  19. Radiation-Induced Cognitive Dysfunction and Cerebellar Oxidative Stress in Mice: Protective Effect of a-Lipoic Acid
    Kailash Manda, Megumi Ueno, Takashi Moritake, and Kazunori Anzai
    Behav. Brain Res., in press.
  20. alpha-Lipoic Acid Attenuates X-Irradiation-Induced Oxidative Stress in Mice
    Kailash Manda, Megumi Ueno, Takashi Moritake, and Kazunori Anzai
    Cell Biol. Toxicol., in press.
  21. High-Resolution Mapping of Tumor Redox Status by Magnetic Resonance Imaging Using Nitroxides as Redox-Sensitive Cntrasta Agents
    Ken-ichiro Matsumoto, Fuminori Hyodo, Atsuko Matsumoto, Alan P. Koretsky, Anastasia L. Sowers, James B. Michell, and Murali C. Krishna
    Clin. Cancer Res., 12 (8), 2455-2462 (2006).
  22. Probing the Intracellular Redox Status of Tumors with Magnetic Resonance Imaging and Redox-Sensitive Contrast Agents
    Fuminori Hyodo, Ken-ichiro Matsumoto, Atsuko Matsumoto, James B. Mitchell, and Murali C. Krishna
    Cancer Res., 66 (20), 9921-9928 (2006).
  23. Drastic Effect of Several Caffeic Acid Derivatives on the Induction of Heme Oxygenase-1 Expression Revealed by Quantitative Real-Time RT-PCR
    Keiko Suzuki, Izumi Tanaka, Ikuo Nakanishi, Ayako Kurematsu, Haruko Yakumaru, Nobuo Ikota, and Hiroshi Ishihara
    Biofactors, 28 (3-4), 151-158 (2006).
  24. Electron Paramagnetic Resonance Decay Constant and Oxidative Stresses in Liver Microsomes of the Selenium-Deficient Rat
    Ken-ichiro Matsumoto, Ayako Suzuki, Haruka Washimi, Atsushi Hisamatsu, Aya Okajo, Iori Ui, and Kazutoyo Endo
    J. Nutr. Biochem., 17 (10), 677-681 (2006).
  25. Competition of Nitroxyl Contrast Agents As an In Vivo Tissue Redox Probe: Comparison of Pharmacokinetics by the Bile Flow Monitoring (BFM) and Blood Circulating Monitoring (BCM) Methods Using X-Band EPR and Simulation of Decay Profiles
    Aya Okajo, Ken-ichiro Matsumoto, James B. Michell, Murali C. Krishna, and Kazutoyo Endo
    Magn. Reson. Med., 56, 422-431 (2006).
  26. MR Assessment of Changes of Tumor in Response to Hyperbaric Oxygen Treatment
    Ken-ichiro Matsumoto, Marcelino Bernardo, Sankaran Subramanian, Peter Choyke, James B. Mitchell, Murali C. Krishna, and Martin J. Lizak
    Magn. Reson. Med., 56, 240-246 (2006).
  27. Planar Catechin Analogues with Alkyl Side Chain, a Potent Antioxidant and an alpha-Glucosidase Inhibitor
    Wataru Hakamata, Ikuo Nakanishi, Yu Masuda, Takehiko Shimizu, Hajime Higuchi, Yuriko Nakamura, Tadatake Oku, Sinichi Saito, Shiro Urano, Toshihiko Ozawa, Nobuo Ikota, Naoki Miyata, Haruhiro Okuda, and Kiyoshi Fukuhara
    J. Am. Chem. Soc., 128 (20), 6524-6525 (2006).
  28. Structural Basis for DNA-Cleaving Activity of Resveratrol in the Presence of Cu(II)
    Kiyoshi Fukuhara, Maki Nagakawa, Ikuo Nakanishi, Kei Ohkubo, Kohei Imai, Shiro Urano, Shunichi Fukuzumi, Toshihiko Ozawa, Nobuo Ikota, Masataka Mochizuki, Naoki Miyata, and Haruhiro Okuda
    Bioorg. Med. Chem., 14 (5), 1437-1443 (2006).
  29. Comparison of Stable Nitroxide, 3-Substituted 2,2,5,5-Tetramethylpyrrolidine-N-oxyls, with Respect to Protection from Radiation, Prevention of DNA Damage, and Distribution in Mice
    Kazunori Anzai, Megumi Ueno, Akira Yoshida, Masako Furuse, Winn Aung, Ikuo Nakanishi, Takashi Moritake, Keizo Takeshita, and Nobuo Ikota
    Free Radical Biol. Med., 40 (7), 1170-1178 (2006). DOI: 10.1016/j.freeradbiomed.2005.11.006

Updated on 2008.1.10
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