Updated on 4/7/08

Dr. Sushma Manda

Visiting Collaborative Researcher
Radiation Modifier Team
Heavy-Ion Radiobiology Research Group
Research Center for Charged Particle Therapy
National Institute of Radiological Sciences (NIRS)
Academic Qualifications
  • Ph.D. (2004; Field of Electroanalytical Chemistry)-Department of Chemistry, University of Rajasthan, Jaipur, Rajasthan, India
    Title of Thesis: Trace Analysis of Toxic Metals and Harmful Organics in Industrial Effluent, Potable Water Sources and Edibles by Modern Voltammetric Techniques
  • M.Sc. (1999; 1st Class; COSIST course in Chemistry)-Department of Chemistry, University of Rajasthan, Jaipur, Rajasthan, India
  • B.Sc. (1996; 1st Class; CBZ course)-M.D.S. University, Ajmer, Rajasthan, India
Experience
  • Visiting Collaborative Researcher-December 2007-May 2008
    National Institute of Radiological Sciences (NIRS), Chiba, Japan
  • Visiting Collaborative Researcher-February 2006-October 2007
    National Institute of Radiological Sciences (NIRS), Chiba, Japan
  • Senior Research Fellow (CSIR)-2004
    IPC Department, Indian Institute of Science, Bangalore, India
  • Senior Research Fellow (CSIR)-2003
    Department of Chemistry, University of Rajasthan, Jaipur, Rajasthan, India
  • Junior Research Fellow (CSIR)-2001-2002
    Department of Chemistry, University of Rajasthan, Jaipur, Rajasthan, India
Awards
  • First Position at Distinct Level in B.Sc.
  • CSIR-NET-JRF (June 2000)
  • CSIR SRF (January 2002-December 2004)
Papers
  1. Scandium Ion-accelerated Scavenging Reaction of Cumylperoxyl Radical by a Cyclic Nitroxyl Radical via Electron Transfer
    Ikuo Nakanishi, Kumiko Kawaguchi, Kei Ohkubo, Tomonori Kawashima, Sushma Manda, Hideko Kanazawa, Keizo Takeshita, Kazunori Anzai, Toshihiko Ozawa, Shunichi Fukuzumi, and Nobuo Ikota
    Chem. Lett., 36 (3), 378-379 (2007). DOI: 10.1246/cl.2007.378
  2. Effect of Solvent Polarity on the One-electron Oxidation of Cyclic Nitroxyl Radicals
    Sushma Manda, Ikuo Nakanishi, Kei Ohkubo, Tomonori Kawashima, Ken-ichiro Matsumoto, Toshihiko Ozawa, Shunichi Fukuzumi, Nobuo Ikota, and Kazunori Anzai
    Chem. Lett., 36 (7), 914-915 (2007). DOI: 10.1246/cl.2007.914
  3. Involvement of Electron Transfer in the Radical-Scavenging Reaction of Resveratrol
    Ikuo Nakanishi, Tomokazu Shimada, Kei Ohkubo, Sushma Manda, Takehiko Shimizu, Shiro Urano, Haruhiro Okuda, Naoki Miyata, Toshihiko Ozawa, Kazunori Anzai, Shunichi Fukuzumi, Nobuo Ikota, and Kiyoshi Fukuhara
    Chem. Lett., 36 (10), 1276-1277 (2007). DOI: 10.1246/cl.2007.1276
  4. Nitroxyl Radicals: Electrochemical Redox Behaviour and Structure-Activity Relationships
    Sushma Manda, Ikuo Nakanishi, Kei Ohkubo, Haruko Yakumaru, Ken-ichiro Matsumoto, Toshihiko Ozawa, Nobuo Ikota, Shunichi Fukuzumi, and Kazunori Anzai
    Org. Biomol. Chem., 5 (24), 3951-3955 (2007). DOI: 10.1039/b714765a
  5. Enhanced Radical-Scavenging Activity of Naturally-Oriented Artepillin C Derivatives
    Sushma Manda, Ikuo Nakanishi, Kei Ohkubo, Yoshihiro Uto, Tomonori Kawashima, Kiyoshi Fukuhara, Haruhiro Okuda, Hitoshi Hori, Toshihiko Ozawa, Nobuo Ikota, Shunichi Fukuzumi, and Kazunori Anzai
    Chem. Commun., 2008, 626-628. DOI: 10.1039/b715973k
  6. In vivo Redox Environments Beleaguering Nitroxyl Radioprotectors in Liver and Blood under Oxidative Atmosphere
    Aya Okajo, Iori Ui, Sushma Manda, Ikuo Nakanishi, Ken-ichiro Matsumoto, Kazunori Anzai, and Kazutoyo Endo
    In preparation.

Proceedings

  1. Redox Behavior of Nitroxide Spin Probes in the Presence of Metal Irons
    Tomonori Kawashima, Ikuo Nakanishi, Kumiko Kawaguchi, Kei Ohkubo, Sushma Manda, Hideko Kanazawa, Kazunori Anzai, Shunichi Fukuzumi, Toshihiko Ozawa, and Nobuo Ikota
    J. Pharm. Soc. Jpn., 126 (Suppl. 1), P-14 (2006).
  2. Kinetic Study on the Radical-Scavenging Activity of Natural Antioxidants Having 4-Propenylphenol Structures
    Tomonori Kawashima, Ikuo Nakanishi, Kei Ohkubo, Yoshihiro Uto, Sushma Manda, Hideko Kanazawa, Kiyoshi Fukuhara, Haruhiro Okuda, Keiko Suzuki, Hideko Nagasawa, Hitoshi Hori, Kazunori Anzai, Toshiniko Ozawa, Shunichi Fukuzumi, and Nobuo Ikota
    Free Radical Res., 40 (S1), S102 (2006).
  3. Radical-Scavenging Activity of Nitroxide Radical as an Electron Donor
    Kumiko Kawaguchi, Ikuo Nakanishi, Kei Ohkubo, Tomonori Kawashima, Sushma Manda, Hideko Kanazawa, Keizo Takeshita, Kazunori Anzai, Toshihiko Ozawa, Shunichi Fukuzumi, and Nobuo Ikota
    Free Radical Res., 40 (S1), S165 (2006).
  4. Kinetic Study on the Radical-Scavenging Activity of Natural Antioxidants Having 4-Propenylphenol Structures
    Tomonori Kawashima, Ikuo Nakanishi, Kei Ohkubo, Yoshihiro Uto, Sushma Manda, Hideko Kanazawa, Kiyoshi Fukuhara, Haruhiro Okuda, Keiko Suzuki, Hideko Nagasawa, Hitoshi Hori, Kazunori Anzai, Toshiniko Ozawa, Shunichi Fukuzumi, and Nobuo Ikota
    "XIII Congress of the Society for Free Radical Research International," International Proceedings, Medimond, Italy (2006), pp.199-201.
  5. Radical-Scavenging Activity of Nitroxyl Radical as an Electron Donor
    Sushma Manda, Kumiko Kawaguchi, Kei Ohkubo, Tomonori Kawashima, Hideko Kanazawa, Keizo Takeshita, Kazunori Anzai, Toshihiko Ozawa, Shunichi Fukuzumi, Nobuo Ikota, and Ikuo Nakanishi
    "XIII Congress of the Society for Free Radical Research International," International Proceedings, Medimond, Italy (2006), pp.237-239.
  6. Scavenging Activity of Cumylperoxyl Radical by Artepillin C and Its Derivatives
    Ikuo Nakanishi, Yoshihiro Uto, Kei Ohkubo, Tomonori Kawashima, Sushma Manda, Hideko Kanazawa, Hideko Nagasawa, Hitoshi Hori, Haruhiro Okuda, Kiyoshi Fukuhara, Toshihiko Ozawa, Nobuo Ikota, Shunichi Fukuzumi, and Kazunori Anzai
    Lipid Peroxide Research, 30, 62 (2006).
  7. Radical-Scavenging Reactions of 4-Propenylphenol Derivatives
    Tomonori Kawashima, Ikuo Nakanishi, Kei Ohkubo, Yoshihiro Uto, Sushma Manda, Keiko Suzuki, Hideko Kanazawa, Kiyoshi Fukuhara, Haruhiro Okuda, Hideko Nagasawa, Hitoshi Hori, Kazunori Anzai, Toshihiko Ozawa, Nobuo Ikota, and Shunichi Fukuzumi
    Free Radical Biol. Med., 41 (S1), S23 (2006).
  8. DNA Cleaving-Activity of Water-Soluble C70 under Visible-Light Irradiation
    Ikuo Nakanishi, Kei Ohkubo, Tomonori Kawashima, Kumiko Kawaguchi, Minako Nyui, Mitsuko Takusagawa, Sushma Manda, Tomoyoshi Suenobu, Kiyoshi Fukuhara, Haruhiro Okuda, Hideko Kanazawa, Naoki Miyata, Toshihiko Ozawa, Kazunori Anzai, Shunichi Fukuzumi, and Nobuo Ikota
    Free Radical Biol. Med., 41 (S1), S66 (2006).
  9. Enhanced Radical-Scavenging Activity of Artepillin C Derivatives
    Ikuo Nakanishi, Kei Ohkubo, Yoshihiro Uto, Tomonori Kawashima, Sushma Manda, Hideko Kanazawa, Hitoshi Hori, Kiyoshi Fukuhara, Haruhiro Okuda, Toshihiko Ozawa, Nobuo Ikota, Shunichi Fukuzumi, and Kazunori Anzai
    FASEB J., 21 (6), lb373 (2007).
  10. Effect of Bio-Related Metal Ions on the Radical-Scavenging Reactions by Curcumin
    Tomonori Kawashima, Ikuo Nakanishi, Kei Ohkubo, Sushma Manda, Kiyoshi Fukuhara, Haruhiro Okuda, Toshihiko Ozawa, Nobuo Ikota, Kazunori Anzai, and Shunichi Fukuzumi
    J. Pharm. Soc. Jpn., 127 (Suppl. 2), 76 (2007).
  11. Electron-Transfer Mechanism in the Radical-Scavenging Reaction of Resveratrol
    Ikuo Nakanishi, Tomokazu Shimada, Kei Ohkukbo, Sushma Manda, Shiro Urano, Haruhiro Okuda, Naoki Miyata, Toshihiko Ozawa, Kazunori Anzai, Shunichi Fukuzumi, Nobuo Ikota, and Kiyoshi Fukuhara
    Free Radical Biol. Med., 43 (S1), S17 (2007).
  12. Change in Absolute Oxygen Concentration in Solution after X-Ray Irradiation using Low Field Electron Para Magnetic Resonance Spectroscopy
    Atsuko Matsumoto, Ken-ichiro Matsumoto, Sushma Manda, Megumi Ueno, and Kazunori Anzai
    Free Radical Biol. Med., 43 (S1), S130 (2007).

Meetings

  1. Radical-Scavenging Activity of Natural Antioxidants Having 4-Propenylphenol Structures
    Tomonori Kawashima, Ikuo Nakanishi, Sushma Manda, Yoshihiro Uto, Kei Ohkubo, Hideko Kanazawa, Kiyoshi Fukuhara, Haruhiro Okuda, Hideko Nagasawa, Hitoshi Hori, Kazunori Anzai, Toshihiko Ozawa, Shunichi Fukuzumi, and Nobuo Ikota
    XVth Annual Meeting of the Oxygen Club of California, Santa Barbara, California, USA, March 15-18, 2006.
  2. Radical-Scavenging Activity of Natural and Synthetic 4-Propenylphenol Derivatives
    Tomonori Kawashima, Ikuo Nakanishi, Yoshihiro Uto, Kei Ohkubo, Sushma Manda, Hideko Kanazawa, Kiyoshi Fukuhara, Haruhiro Okuda, Hideko Nagasawa, Hitoshi Hori, Shunichi Fukuzumi, Kazunori Anzai, Toshihiko Ozawa, and Nobuo Ikota
    28th Annual Meeting of the Society for Free Radical Research Japan (SFRR Japan), Mie, May 13, 14, 2006.
  3. Redox Behavior of Nitroxide Spin Probes in the Presence of Metal Ions
    Tomonori Kawashima, Ikuo Nakanishi, Kumiko Kawaguchi, Kei Ohkubo, Sushma Manda, Hideko Kanazawa, Kazunori Anzai, Shunichi Fukuzumi, Toshihiko Ozawa, and Nobuo Ikota
    16th Symposium on Roles of Metals in Biological Reaction, Biology and Medicine (srm2006), Tokyo, June 1, 2, 2006.
  4. Free Radical Scavenging Reactions by Propenylphenol Compounds
    Tomonori Kawashima, Ikuo Nakanishi, Yoshihiro Uto, Keiko Suzuki, Sushma Manda, Hideko Kanazawa, Kiyoshi Fukuhara, Haruhiro Okuda, Hideko Nagasawa, Hitoshi Hori, Shunichi Fukuzumi, Kazunori Anzai, Toshihiko Ozawa, and Nobuo Ikota
    6th Society for the Study of AOB (Antioxidant Biofactor), Sapporo, June 9, 2006
  5. Kinetic Study on the Radical-Scavenging Activity of Natural Antioxidants Having 4-Propenylphenol Structures
    Tomonori Kawashima, Ikuo Nakanishi, Kei Ohkubo, Yoshihiro Uto, Sushma Manda, Hideko Kanazawa, Kiyoshi Fukuhara, Haruhiro Okuda, Keiko Suzuki, Hideko Nagasawa, Hitoshi Hori, Kazunori Anzai, Toshihiko Ozawa, Shunichi Fukuzumi, and Nobuo Ikota
    XIII Biennial Meeting of the Society for Free Radical Research International, Davos, Switzerland, August 15-19, 2006.
  6. Radical-Scavenging Activity of Nitroxide Radical as an Electron Donor
    Kumiko Kawaguchi, Ikuo Nakanishi, Kei Ohkubo, Tomonori Kawashima, Sushma Manda, Hideko Kanazawa, Keizo Takeshita, Kazunori Anzai, Toshihiko Ozawa, Shunichi Fukuzumi, and Nobuo Ikota
    XIII Biennial Meeting of the Society for Free Radical Research International, Davos, Switzerland, August 15-19, 2006.
  7. alpha-Lipoic Acid Ameliorates Radiation-Induced Behavioural Toxicity and Brain Oxidative Stress in Mice
    Kailash Manda, Megumi Ueno, Sushma Manda, Takashi Moritake, Ikuo Nakanishi, and Kazunori Anzai
    The 49th Annual Meeting of the Japan Radiation Research Society, Sapporo, September 6-8, 2006.
  8. Structure-Activity Relationships in the Free Radical-Scavenging Reactions by 4-Propenylphenol Compounds
    Tomonori Kawashima, Ikuo Nakanishi, Yoshihiro Uto, Kei Ohkubo, Keiko Suzuki, Sushma Manda, Hideko Kanazawa, Kiyoshi Fukuhara, Haruhiro Okuda, Hideko Nagasawa, Hitoshi Hori, Shunichi Fukuzumi, Kazunori Anzai, Toshihiko Ozawa, and Nobuo Ikota
    2nd Symposium on Molecular Informational Dynamics, Osaka, September 25, 26, 2006.
  9. Effects of Metal Ions on Radical-Scavenging Activity of Curcumin
    Tomonori Kawashima, Ikuo Nakanishi, Kei Ohkubo, Sushma Manda, Hideko Kanazawa, Haruhiro Okuda, Kiyoshi Fukuhara, Toshihiko Ozawa, Shunichi Fukuzumi, Nobuo Ikota, and Kazunori Anzai
    Kyoto, September 28-30, 2006.
  10. Radical-Scavenging Activity of Artepillin C and Its Derivatives
    Ikuo Nakanishi, Yoshihiro Uto, Kei Ohkubo, Tomonori Kawashima, Sushma Manda, Hideko Kanazawa, Hideko Nagasawa, Hitoshi Hori, Haruhiro Okuda, Kiyoshi Fukuhara, Toshihiko Ozawa, Nobuo Ikota, Shunichi Fukuzumi, and Kazunori Anzai
    Kyoto, September 28-30, 2006.
  11. Scavenging Activity of Cumylperoxyl Radical by Artepillin C and Its Derivatives
    Ikuo Nakanishi, Yoshihiro Uto, Kei Ohkubo, Tomonori Kawashima, Sushma Manda, Hideko Kanazawa, Hideko Nagasawa, Hitoshi Hori, Haruhiro Okuda, Kiyoshi Fukuhara, Toshihiko Ozawa, Nobuo Ikota, Shunichi Fukuzumi, and Kazunori Anzai
    Tokyo, October 20, 21, 2006.
  12. SEST2006
  13. SFRBM2006
  14. SFRBM2006
  15. VE
  16. Solvent Effect on Redox Behavior of Nitroxyl Radicals
    CSJ
  17. Development of Artepillin C Derivatives with Enhanced Antioxidative Activity
    The 127th Annual Meeting of the Pharmaceutical Society of Japan, Toyama, March, 2006.
  18. Effects of Metal Ions on the Radical-Scavenging Reaction of Curcumin
    The 127th Annual Meeting of the Pharmaceutical Society of Japan, Toyama, March, 2006.
  19. Enhanced Radical-Scavenging Activity of Artepillin C Derivatives
    Ikuo Nakanishi, Kei Ohkubo, Yoshihiro Uto, Tomonori Kawashima, Sushma Manda, Hideko Kanazawa, Hitoshi Hori, Kiyoshi Fukuhara, Haruhiro Okuda, Toshihiko Ozawa, Nobuo Ikota, Shunichi Fukuzumi, and Kazunori Anzai
    Experimental Biology Annual Meeting 2007 (EB2007), Washington, D.C., USA, April 28-May 2, 2007.
  20. Development of Novel Antioxidants Based on the Structures of Natural Phenolic Antioxidants
    Ikuo Nakanishi, Kei Ohkubo, Yoshihiro Uto, Tomonori Kawashima, Sushma Manda, Kiyoshi Fukuhara, Haruhiro Okuda, Hitoshi Hori, Nobuo Ikota, Shunichi Fukuzumi, Kazunori Anzai, and Toshihiko Ozawa
    The 7th Meeting of Society for the Study of AOB (Antioxidant Biofactor), Taiwan, June 1, 2007.
  21. Electrochemistry of Cyclic Nitroxyl Radicals. Solvent Effect on the One-Electron Oxidation Potentials
    Sushma Manda, Ikuo Nakanishi, Kei Ohkubo, Tomonori Kawashima, Shunichi Fukuzumi, Toshihiko Ozawa, Nobuo Ikota, and Kazunori Anzai
    29th Annual Meeting of the Society for Free Radical Research, Japan, Nagoya, June 9, 10, 2007.
  22. Effect of Bio-Related Metal Ions on the Radical-Scavenging Reactions by Curcumin
    Tomonori Kawashima, Ikuo Nakanishi, Kei Ohkubo, Sushma Manda, Kiyoshi Fukuhara, Haruhiro Okuda, Toshihiko Ozawa, Nobuo Ikota, Kazunori Anzai, and Shunichi Fukuzumi
    17th Symposium on Roles of Metals in Biological Reactions, Biology and Medicine (SRM2007), Kyoto, June 21, 22, 2007.
  23. Electron-Transfer Mechanism in the Radical-Scavenging Reaction of Resveratrol
    Ikuo Nakanishi, Tomokazu Shimada, Kei Ohkubo, Sushma Manda, Shiro Urano, Haruhiro Okuda, Naoki Miyata, Toshihiko Ozawa, Kazunori Anzai, Shunichi Fukuzumi, and Kiyoshi Fukuhara
    14th Annual Meeting of the Society for Free Radical Biology and Medicine (SFRBM), Washington, D.C., November 14-18, 2007.
  24. Change in Absolute Oxygen Concentration in Solution after X-Ray Irradiation using Low Field Electron Para Magnetic Resonance Spectroscopy
    Atsuko Matsumoto, Ken-ichiro Matsumoto, Sushma Manda, Megumi Ueno, and Kazunori Anzai
    14th Annual Meeting of the Society for Free Radical Biology and Medicine (SFRBM), Washington, D.C., November 14-18, 2007.
  25. Effects of Interaction between Curcumin and Metal Ions on the Radical-Scavenging Reaction
    Tomonori Kawashima, Ikuo Nakanishi, Kei Ohkubo, Sushma Manda, Kiyoshi Fukuhara, Haruhiro Okuda, Toshihiko Ozawa, Nobuo Ikota, Kazunori Anzai, and Shunichi Fukuzumi
    The 4th Joint Meeting of the Society for Free Radical Research Australasia and Japan 2007 (SFRR A+J 2007), The Clock Tower of Kyoto University, December 1-5, 2007.
  26. Nitroxy Radicals: Electrochemical Approach to Structure-Activity Relationships
    Sushma Manda, Ikuo Nakanishi, Kei Ohkubo, Haruko Yakumaru, Ken-ichiro Matsumoto, Toshihiko Ozawa, Nobuo Ikota, Shunichi Fukuzumi, and Kazunori Anzai
    The 22nd Annual Meeting of Kanto Branch of the Society for Free Radical Research, Japan (SFRR Japan), Tokyo, December 14, 2007.
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